What is TB-1000 and TB-500?

A synthetic version of the naturally occurring Thymosin Beta 4 (Tß4), present in virtually all human and animal cells. Thymosin Beta 4 offers many advantages in healing and assisting in overall health.

Benefits of TB-1000 and TB-500 for horses

Veterinarians who have used TB-1000 & TB-500 have reported the following indications and personal results:

  • Increased Muscle Growth
  • Muscle Spasm Relaxation
  • Improved Muscle Tone
  • Enhanced Tissue Repair
  • Helping Maintain Flexibility
  • Reducing Joint Inflammation
  • Increased Muscular Endurance
  • Increased Energy Levels
  • Decreased Recovery Time

What does TB-1000 and TB-500 do?

TB-500/1000 provides rapid surface wound healing with little or no scarring and minimal discomfort. If the animal experiences wound injury, it will benefit from TB-500/1000. As TB-500/1000 heals it at the cellular level, it is natural and rapid. Stem cells play an integral part in wound healing and regeneration of body organs and tissue at the cellular level.

All mammalian animals can benefit from the use of TB-500 or TB-1000. Whether an animal is large or small, a performance animal, a breeding animal or a loved and valued pet. TB-500 and TB-1000 can assist in rapid wound healing and blood vessel regeneration. TB-500 and TB-1000 is known to help diabetes in dogs.

TB4 a natural way to improve health in performance horses

TB-1000 and TB-500 are both natural and approved ways to increase health and strength in horses.  TB-1000 and TB-500 are both naturally found  in the body and are 100% drug free.  TB-1000 and TB-500 will not test or swab.

How TB-1000 and TB-500 works scientifically

One of Tß4’s key mechanisms of action is its ability to regulate the cell-building protein, actin, a vital component of cell structure and movement. Of the thousands of proteins present in cells, actin represents up to 10% of the total proteins which therefore plays a major role in the genetic makeup of the cell.

This potent peptide is a member of the ubiquitous family of 16 related molecules with a high conservation of sequence and localization in most tissues and circulating cells in the body. Tß4 not only binds to actin, but also blocks actin polymerization and is the actin-sequestering molecule in Eukaryota cells.

Tß4 was identified as a gene that was up-regulated four to six fold during early blood vessel formation and found to promote the growth of new blood cells from the existing vessels.

This peptide is present in wound fluid and when administered subcutaneously, it promotes wound healing, muscle building, decreases recovery time of muscles fibers and their cells.

An additional key factor of Tß4 is that it promotes cell migration through a specific interaction with actin in the cell cytoskeletal. It has been demonstrated that a central small amino acid long-actin binding domain has both blood cell reproduction and wound healing characteristics. These characteristics are uncovered by accelerating the migration of endothelial cells and keratinocytes. It also increases the production of extracellular matrix-degrading enzymes.

Tß4 is different from other repair factors, such as growth factors, in that it promotes endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has a very low molecular weight meaning it can travel relatively long distances through tissues.

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